Kickoff meeting of the "New generation of drugs protecting against neurotoxic industrial chemicals (NeuroTICs)" project on Thursday 3rd June 2021 at 3:00 pm (CET)
G5852 - New generation of drugs protecting against neurotoxic industrial chemicals
Date: Thursday 3rd June 2021
Time: 3:00 pm (CET)
Duration: 2 hours
Venue: Online meeting
Human brain is a great target for chemical terrorism, so NATO nations should be prepared to respond effectively to terrorist threats involving neurotoxic industrial chemicals (neuroTICs). The main objective of this project is to assess the therapeutic potential of AD4 and thioredoxin-mimetic peptides, blood-brain barrier permeable drugs targeting oxidative stress, apoptosis and inflammation, on acute neurotoxic syndromes induced by three common TICs (organophosphorus compounds, acrylamide, organic mercury). Moreover, specific combinations of drugs derived from the analysis of potential therapeutic targets for each toxidrome will be also tested.